Food52: Countdown To Thanksgiving: What To Prep Monday

Make this brandy-spiked cranberry sauce and let it mellow until Thursday. In this cranberry sauce, you won't find any of the punishing tartness you get in many -- it's all silk and fragrance. The pears, which are shredded, melt into the sauce. The cranberries soften and soak up the brown sugar and cinnamon. And the brandy smoothes any wrinkles. You add a little brandy in the beginning and some more at the very end, as you stir in toasted walnuts. We've made the sauce with grated apple and it's just as delicious. We've also served it over fresh ricotta -- make sure you have some leftovers so you can try this! - Amanda & Merrill Get the recipe. Photo: Sarah Shatz

Source: http://www.huffingtonpost.com/food-52/thanksgiving-prep-guide_b_1096061.html

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98% Le Havre

Saw the Kaurismäki movie Le Havre last night. Besides being set in industrial France, I found it differed hardly an iota from his films set among the down-trodden in industrial Finland. Unfortunately, despite the low key comedy and the sometimes charming art direction, I think his last few works have been rather unsatisfying rehashes of his standard cinematic elements (funny folk music, working class bars, klutzy and ironic agents of social control such as police and lawyers, hapless characters), without being fresh enough, or interesting enough, to merit his audience's attention. I hope he breaks out of his rut in whatever later films he makes. If you've never seen a Kaurismäki film, you might enjoy this minimally, but his previous work is better. Two in particular which encompass his worldview in a more interesting fashion are The Match Factory Girl and The Man without a Past.

November 18, 2011

Source: http://www.rottentomatoes.com/m/le_havre_2011/

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15 films chosen for Oscars documentary shortlist (Reuters)

LOS ANGELES (Reuters) ? The Academy of Motion Picture Arts and Sciences has selected its shortlist of documentary features that will vie for an Oscar.

The 15 titles announced on Friday include "Pina," Wim Wenders' 3D tribute to late choreographer Pina Bausch; "Project Nim," the story of a 1970s behavioral project involving a chimpanzee; AIDS-themed chronicle "We Were Here" and "Buck," a portrait of the man who inspired "The Horse Whisperer."

A couple of war-themed films made the cut: "Hell and Back Again" and "Under Fire: Journalists in Combat," while "Semper Fi: Always Faithful" centers on a career military man who exposes a Marine Corps cover-up of an environmental crisis.

Among The highly regarded documentaries that didn't make the shortlist are Werner Herzog's look at capital punishment, "Into the Abyss," and Steve James's "The Interrupters," an exploration of grassroots attempts to curb urban violence.

For the preliminary round of voting, the Documentary Branch Screening Committee viewed 124 feature-length nonfiction films that qualified in the category. Documentary Branch members will select five nominees from the 15-title shortlist.

Nominations for the 84th Academy Awards will be announced on January 24. The awards ceremony is scheduled for February 26.

The Academy's documentary shortlist, in alphabetical order:

"Battle for Brooklyn"

"Bill Cunningham New York"

"Buck"

"Hell and Back Again"

"If a Tree Falls: A Story of the Earth Liberation Front"

"Jane's Journey"

"The Loving Story"

"Paradise Lost 3: Purgatory"

"Pina"

"Project Nim"

"Semper Fi: Always Faithful"

"Sing Your Song"

"Undefeated"

"Under Fire: Journalists in Combat"

"We Were Here"

(Reporting by Sheri Linden; Editing by David Bailey)

Source: http://us.rd.yahoo.com/dailynews/rss/movies/*http%3A//news.yahoo.com/s/nm/20111121/en_nm/us_oscars_documentary

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Discovery of new muscle repair gene

[ Back to EurekAlert! ] Public release date: 20-Nov-2011
[ | E-mail | Share Share ]

Contact: Paula Gould
p.a.gould@leeds.ac.uk
44-113-343-8059
University of Leeds

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques.

The work, which was co-led from the University of Leeds' School of Medicine and the Charit, Berlin, is published this week in the journal Nature Genetics.

The researchers investigated several families whose children suffered from a progressive muscle disease. The children developed severe weakness of the body's muscles and the diaphragm - the main breathing muscle - making them dependent on a wheelchair and continuous mechanical ventilation. The children also had to be tube-fed because the esophagus - a muscular tube that transports food from the mouth down into the stomach - did not work properly.

Using state-of the-art, next generation DNA sequencing technology, the scientists initially found a defect in the MEGF10 gene for a large family living in the UK. Further work found mutations in families with a similar condition from Europe and Asia.

Their work means that accurate genetic testing and diagnosis will now be possible for this devastating condition.

The MEGF10 gene normally plays an important function in muscle stem cells. These are also called 'satellite cells', because they are attached to the outer surface of the muscle fibres, where they normally remain silent. If a muscle fibre becomes damaged, the satellite cells become active, start to divide and then fuse with the muscle fibre. MEGF10 has an important role in this fusion process because it provides the 'gluey' surface for the attachment of the satellite cell.

Since body muscles make up about 40% of our weight and are the largest organ in the body, the muscles need to be maintained during normal life. MEGF10 also has a role in this regeneration process; failure causes progressive muscle weakness in not only muscles of the body and limbs but also the muscle cells that can be found in the internal organs.

The project's joint directors, Professor Markus Schuelke from the NeuroCure Clinical Research Center and the Department of Neuropediatrics of the Charit, and Professor Colin A. Johnson from the Leeds Institute of Molecular Medicine, University Leeds, emphasized the relevance of the new methods for genomic analysis. They commented: "These methods enable us to sequence hundreds or even thousands of genes at the same time for an affordable price. This enables clinicians and researchers to discover novel genetic defects even in single patients. This is good news for families with unsolved rare genetic disorders. Many affected patients and their parents, who often have a "diagnostic Odyssey" behind them, may now hope that the cause of their disease will be found in the near future."

###

For more information:

Contact: Paula Gould, University of Leeds Communications & Press Office: Tel 44-113-343-8059, email p.a.gould@leeds.ac.uk

The paper, Logan et al. Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD) is published in Nature Genetics 2011 Nov 20, doi: 10.1038/ng.995.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


[ Back to EurekAlert! ] Public release date: 20-Nov-2011
[ | E-mail | Share Share ]

Contact: Paula Gould
p.a.gould@leeds.ac.uk
44-113-343-8059
University of Leeds

An international team of researchers from Leeds, London and Berlin has discovered more about the function of muscle stem cells, thanks to next-generation DNA sequencing techniques.

The work, which was co-led from the University of Leeds' School of Medicine and the Charit, Berlin, is published this week in the journal Nature Genetics.

The researchers investigated several families whose children suffered from a progressive muscle disease. The children developed severe weakness of the body's muscles and the diaphragm - the main breathing muscle - making them dependent on a wheelchair and continuous mechanical ventilation. The children also had to be tube-fed because the esophagus - a muscular tube that transports food from the mouth down into the stomach - did not work properly.

Using state-of the-art, next generation DNA sequencing technology, the scientists initially found a defect in the MEGF10 gene for a large family living in the UK. Further work found mutations in families with a similar condition from Europe and Asia.

Their work means that accurate genetic testing and diagnosis will now be possible for this devastating condition.

The MEGF10 gene normally plays an important function in muscle stem cells. These are also called 'satellite cells', because they are attached to the outer surface of the muscle fibres, where they normally remain silent. If a muscle fibre becomes damaged, the satellite cells become active, start to divide and then fuse with the muscle fibre. MEGF10 has an important role in this fusion process because it provides the 'gluey' surface for the attachment of the satellite cell.

Since body muscles make up about 40% of our weight and are the largest organ in the body, the muscles need to be maintained during normal life. MEGF10 also has a role in this regeneration process; failure causes progressive muscle weakness in not only muscles of the body and limbs but also the muscle cells that can be found in the internal organs.

The project's joint directors, Professor Markus Schuelke from the NeuroCure Clinical Research Center and the Department of Neuropediatrics of the Charit, and Professor Colin A. Johnson from the Leeds Institute of Molecular Medicine, University Leeds, emphasized the relevance of the new methods for genomic analysis. They commented: "These methods enable us to sequence hundreds or even thousands of genes at the same time for an affordable price. This enables clinicians and researchers to discover novel genetic defects even in single patients. This is good news for families with unsolved rare genetic disorders. Many affected patients and their parents, who often have a "diagnostic Odyssey" behind them, may now hope that the cause of their disease will be found in the near future."

###

For more information:

Contact: Paula Gould, University of Leeds Communications & Press Office: Tel 44-113-343-8059, email p.a.gould@leeds.ac.uk

The paper, Logan et al. Mutations in MEGF10, a regulator of satellite cell myogenesis, cause early onset myopathy, areflexia, respiratory distress and dysphagia (EMARDD) is published in Nature Genetics 2011 Nov 20, doi: 10.1038/ng.995.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-11/uol-don111811.php

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Fight For It (Interest Check)

Fight for what you believe in, because otherwise you'll have nothing worth fighting for...

Okay, so I'm re-reading the Inheirtance series, which kinda gave me the idea for this roleplay. This and Monster by Paramore. Criticsm Welcome.

This is just a base idea, it probably needs developing a little more. Help is also appreciated.

There are teenagers all over the world who feel... different, somehow. They feel a pull towards swords. They never quite fit in, while they may have lots of friends. They will fight for their beliefs, whether in a debate or with their friends. They think it's their personality.

But it's their destiny.

On the fourth week of the fourth month, they disappear. They are replaced by a doppelg?nger so nobody misses them. They're not coming back.

They are transported to a weird, unfamiliar world. In some ways, it is extremely technologically advanced in some ways, yet it is far beyond our society in others. Gas lights line the streets and throw shadows onto the streamlined horse drawn coaches.

Yet, while the world seems like a wondering, interesting place, it is in disarray. A tyrant rules who doesn't allow women to learn, work, vote, drive, or own land. They are nothing more than pets, almost. Most of the teenagers are feminists, so this really annoys them. A rebel leader takes them in and teaches them to fight. They want them to fight, to overthrow the tyrant. And then, if they succeed, the leader wants them to be the peacekeepers. But the morals and religous beliefs of the teenagers will make things a lot harder...

I know it needs developing, but it's a start. :)

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/P4pHJlw7HuA/viewtopic.php

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Militia warning as Libyan PM forms government (Reuters)

TRIPOLI (Reuters) ? A commander of Libyan former rebels has warned that his men could overthrow the incoming government if it fails to meet their demands for representation.

The credibility of the threat, made by Tripoli militia leader Abdullah Naker in a Reuters interview, was hard to assess in a city where the balance of forces, three months after the fall of Muammar Gaddafi, is obscure and fluid.

Critics dismissed it as posturing. But it highlighted the tensions, and the high stakes, on Thursday as Abdurrahim El-Keib, the U.S.-trained engineering professor nominated as interim prime minister by the National Transitional Council, tries to agree a cabinet line-up by a Tuesday deadline.

"We are still here on the ground and the final decision will be ours," said Naker, speaking late on Wednesday at his base in the headquarters of a state-owned construction company as some of the thousands of armed men he says he has at his disposal prepared for night-time security patrols in the city.

Demanding Keib appoint ministers who would represent the young rebels who ousted the old order, Naker, leader of the Tripoli Revolutionary Council said his men would protest nationwide, peacefully "at first" if they did not like the new cabinet, as they did against Gaddafi.

"If we find we have the same dictatorship, we will respond in the same way," he said, showing off video of his men firing Grad missiles and driving Soviet-build T-72 tanks during the war. "It will not be an armed movement at first, but it might develop into that. There's a strong possibility that it will."

NTC officials and fighters from other units played down the influence wielded by Naker, an engineer from the mountain town of Zintan who vowed to return to civilian life once democracy and security were assured. But in a state with no police or army, forming a government to satisfy the competing interests of tens of thousands of armed men is a fraught process.

MILITIA POWER

Outgoing prime minister Mahmoud Jibril has sounded an alarm about a "power vacuum" that may be exploited by armed groups.

Western and Middle Eastern diplomats in the capital tend to play down the risk of a sudden flare-up in violence - many of the armed former rebels are simply keen to see a government installed that will allow them to return to civilian life.

Many diplomats believe a competent cabinet will be formed next week, if not necessarily within the deadline, by Keib, who has won admirers among Libyans and foreigners for his apparent openness to compromise. But as Keib himself has said, stable government will require bringing power into the hands of new security forces and disarming militias.

"Political power is really now in the hands of the militias," said George Joffe, a North Africa specialist at Cambridge University. "Keib ... is having to listen to a million different factions all saying they want a piece of the pie. Behind them stand the militias."

Keib has described Tuesday's deadline as a "soft constraint" - set at 30 days after the NTC declared all Libya "liberated" following Gaddafi's killing - and says his priority is to bring in competent technocrats to run the oil-rich state and organize elections by June to a constitutional assembly.

"The main thing is competence," he said last week, stressing the short shelf-life of the new government.

BALANCING INTERESTS

Yet with few political parties to speak of after 42 years of dictatorship but a host of local paramilitary units from across Libya staking claims to a share of power by their presence in the capital, those involved acknowledge that his cabinet must satisfy a complex balance of regional interests.

Among the trickiest tasks - notably in choosing ministers of defense and interior - may be satisfying demands from cities like Misrata, Benghazi and Zintan, which feel a keen sense of entitlement deriving from their roles in the war on Gaddafi.

Keib must also handle potentially vigorous opposition to figures seen as too close to the old regime, as well as rivalry between overtly secular leaders and Islamists viewed by their opponents as overly indebted to foreign backers, namely Qatar.

Though not alone in his objections, militia leader Naker placed particular emphasis on rejecting any role in government for Abdul Hakim Belhadj, the Islamist and former Taliban ally in Afghanistan whom the NTC named as Tripoli military leader.

Belhadj himself dismisses suggestions that he and his ally, Qatar-based cleric Ali al-Sallabi, are agents of the Gulf state which poured military and humanitarian aid into the rebel camp, but their opponents remain unconvinced.

"We are really grateful to Qatar for what they did for the Libyan people," Naker said. But, describing the brand of Islam favored by Belhadj as unsuited to Libya's "moderate" religion, he added: "They have no right to interfere in our affairs. We will not accept domination by Qatar or by anyone else."

Figures close to the NTC - in the fluid environment of the change of government, channels of information are unclear - said they expected Keib to present a draft government list to the Council on Saturday or Sunday, though this might include many alternative choices for different ministries.

Officials and foreign diplomats said Keib seemed to have succeeded in keeping his preferences under wraps, while he faced lobbying from rival groups, notably regional militias, particularly over key ministries like defense and over the choice of a new chief-of-staff for the armed forces.

(Additional reporting by Taha Zargoun; Editing by Matthew Jones)

Source: http://us.rd.yahoo.com/dailynews/rss/world/*http%3A//news.yahoo.com/s/nm/20111117/wl_nm/us_libya_government

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Tamayo tops Latam auction, kinetic art sales strong (Reuters)

NEW YORK (Reuters) ? Rufino Tamayo's painting "Watermelon Slices" fetched $2.2 million, topping Sotheby's Latin American sale, which also set auction records for pioneering Venezuelan kinetic artist Carlos Cruz-Diez.

"It was a great night for Rufino Tamayo," Sotheby's Latin American art chief Carmen Melian said of the Wednesday evening sale, which totaled $17 million.

"Watermelon Slices is a symphony of colors that recall the (late U.S. master abstract colorist) Mark Rothko. Dozens and dozens of reds and orange shades vibrate," she said.

Melian added that the work, which shows watermelon slices precariously balanced on a brown stand, is difficult to reproduce because Tamayo used pure dried pigment for each tone.

The painting, which was sold by The Museum of Modern Art for its acquisition fund, held a personal significance for Tamayo, Sotheby's said. As a boy, he helped his aunt sell watermelons at a Mexico City market stand.

Tamayo, who died in 1991, is widely seen as a monumental figure of Mexican 20th century art. The Sotheby's auction also fetched unusually hefty prices for work from a long overlooked earlier period when he explored surrealism.

The 1928 "Frutero y Domino" fetched $530,500 and the 1932 "La Tenista" sold for $398,500.

Among other highlights was kinetic art, which "had an exceptional night," said Melian.

Kinetic art plays on optical illusion. Typically, works seem to vibrate for viewers walking past.

Venezuelans played an early and prominent role in developing the genre. Among them was Cruz-Diez, whose 1962 "Physichromie 88" set an auction record at $518,500.

Featuring cardboard on wood, the work at first seems to display what looks like a miniature multicolored skyline. But shapes can turn solid black depending on the viewing angle.

Fellow Venezuelan kinetic artist Jesus Rafael Soto's 1976 "Escritura Cobalto" fetched $530,500.

Bids for kinetic art came from around the world, said Axel Stein, Sotheby's vice president. Explaining its global appeal, he said the genre bears the "universal language of geometry."

"You can be Russian, Latin American, French, it's abstract you get it or you don't," he said. "It's also playful."

The auction also set records for Mexican artist Francisco Corzas for his oil on canvas of a nude young woman "Desnudo (Fleur du Mal") which sold for $218,500.

Argentine artist Martha Boto's "Abstraccion No. 3" sold for $56,250, setting an auction record for her painting.

(Reporting by Walker Simon; editing by Patricia Reaney)

Source: http://us.rd.yahoo.com/dailynews/rss/latam/*http%3A//news.yahoo.com/s/nm/20111117/lf_nm_life/us_art_auction_latam

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Sveum introduced as Cubs' 52nd manager

Chicago Cubs general manager Jed Hoyer, left, and president Theo Epstein, right, help new manager Dale Sveum put on Cubs jersey as he is introduced during a baseball news conference, Friday, Nov. 18, 2011, in Chicago. (AP Photo/M. Spencer Green)

Chicago Cubs general manager Jed Hoyer, left, and president Theo Epstein, right, help new manager Dale Sveum put on Cubs jersey as he is introduced during a baseball news conference, Friday, Nov. 18, 2011, in Chicago. (AP Photo/M. Spencer Green)

Dale Sevum addresses the media after being introduced as the new manager of the Chicago Cubs baseball club during a news conference, Friday, Nov. 18, 2011, in Chicago. AP Photo/M. Spencer Green)

Chicago Cubs general manager Jed Hoyer, left, and president Theo Epstein, right, introduce new manager Dale Svem during a baseball news conference, Friday, Nov. 18, 2011, in Chicago. (AP Photo/M. Spencer Green)

Dale Sveum addresses the media after being introduced as the new manager of the Chicago Cubs baseball club during a news conference, Friday, Nov. 18, 2011, in Chicago. AP Photo/M. Spencer Green)

Dale Sevum dons a Chicago Cubs jersey after being introduced as the new manager of the baseball club during a news conference, Friday, Nov. 18, 2011, in Chicago. AP Photo/M. Spencer Green)

(AP) ? Dale Sveum's approach is low-key and universal. He can converse with the clubhouse attendant, relate to the 25th man on the roster and chat up the multimillionaire-dollar star.

He'll demand as much accountability from the Chicago Cubs' veterans as he will from the younger ones. Whining will not be tolerated. Ground balls will be run out at full speed. And he'll address problems directly ? face-to-face.

"We wouldn't have brought him into the interview if he wasn't so well-respected by all the players he's been around," Cubs general manager Jed Hoyer said when Sveum was introduced Friday as the team's new manager.

Now, of course, the big question: Can he win?

Sveum was courted by two teams with great traditions, and he landed with the one with the current long championship drought.

He was interviewed twice by both the Red Sox and the Cubs. When Chicago made an offer two days ago at the owners/GM meetings in Milwaukee, he was finally in reach of the managerial job he'd been thinking about since his playing days were winding down in the late 1990s.

"I think the arrow fell in the right spot. Whenever you got two places like that and you're in the running, your head is spinning a little bit," Sveum said. "I think what it came down to (is) this was just the better fit."

Sveum will be staying in the NL Central. He has been Milwaukee's hitting coach the last three seasons and also served as bench and third base coach with the Brewers, the team that launched his 12-year major league career in 1986. And he's had a strong relationship with Brewers star Prince Fielder, one of the biggest free agents this offseason.

Sveum's lone big league managerial experience lasted 16 games ? 12 at the end of the regular season in 2008 after Ned Yost was fired and four in the playoffs after the Brewers captured that wild card that season. But he was passed up twice for the full-time job as Milwaukee went with Ken Macha, then Ron Roenicke.

Sveum also managed the Pirates' Double-A team before he became Boston's third base coach in 2004, the year it ended an 86-year championship drought by taking the World Series.

The Cubs haven't won one since 1918.

"The past is the past no matter where you are," Sveum said during an introductory news conference at Wrigley Field. "You're only as good as you are right now. It doesn't really matter what happened in the past. ... The 103, 104 years blah, blah. It was that way in Boston, it was 86 years. We all know that, but the fact of the matter is when take the field the first day of spring training, it's a whole new year."

Sveum received a three-year deal with an option for 2015 as the Cubs continue to revamp their operation. Theo Epstein was Boston's general manager before he left last month to become the Cubs' president of baseball operations, and Hoyer and scouting director Jason McLeod also worked for the Red Sox.

"Dale won't get caught up in the trappings of the job," Epstein said. "He's very comfortable in his own skin."

Sveum replaces the fired Mike Quade. Also interviewed were Rangers pitching coach Mike Maddux, Phillies bench coach Pete Mackanin and Indians bench coach Sandy Alomar Jr.

This past season under first-year manager Roenicke, the Brewers won 96 games and the NL Central as Sveum supervised one of the best offenses in the National League. With Ryan Braun and Fielder leading the way, the Brewers hit an NL-high 185 homers and were third with a .261 batting average on their way to the NL Central title ? well ahead of the fifth-place Cubs.

The switch-hitting Sveum was an infielder during a long major league career that included 25 homers and 95 RBIs in 1987. He was injured in an outfield collision the following season, then missed the 1989 season and was never the same player.

Sveum got to play under some of the marquee managers in the game, including Joe Torre, Tony La Russa and Jim Leyland. Each had an effect on how he plans to approach his new job.

"I think the one common thread is the ability to motivate and none of them were screamers or yellers," Sveum said.

"Their ability on the bench to never show any emotion or body language ? bad body language or good body language ? I think that's a big asset to show players. That even though it might be crunch time or whatever, they still seemed to be calm and bring an ease to the team."

Even though he says he hasn't read the book, "Moneyball," or seen the movie, Sveum is a proponent of statistical analysis favored by Epstein during his years in Boston, saying it gives the manager options when studying matchups and filling out lineups. And he'll talk baseball for hours.

Sveum was ready to start meeting with coaching staff holdovers after his news conference on a cold morning at Wrigley Field.

He's promised to improve the defense ? the Cubs made 134 errors while losing 91 games last season ? and baserunning Like everyone else, he was impressed with the offensive skills of 21-year old Cubs shortstop Starlin Castro, who had 207 hits a year ago.

He wants a bench coach whom he knows well because they are bound to tangle during the season. But it won't be former Brewers Hall of Famer Robin Yount, whom he calls his best friend.

"That's not going to happen," Sveum said.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/347875155d53465d95cec892aeb06419/Article_2011-11-18-Cubs-Sveum/id-5fe652523ce140c684d6f6d094b793b5

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